Ion channels as antivirus targets
X Liang, Z Li - Virologica Sinica, 2010 - Springer
… a group of viral channel proteins that … channel-forming proteins may be “lethal”, which can
be a suitable and potential therapeutic strategy. In this review we discuss seven ion channels …
be a suitable and potential therapeutic strategy. In this review we discuss seven ion channels …
Coronaviral ion channels as target for Chinese herbal medicine
… that viral ion channels, in general, may be good targets for the development of antiviral agents,
… of known antiviral phytochemicals on the ionchannel-forming 3a protein of coronavirus. …
… of known antiviral phytochemicals on the ionchannel-forming 3a protein of coronavirus. …
Viral dependence on cellular ion channels–an emerging anti-viral target?
… targeting ion channels pharmacologically can impede virus life cycles. Here, we discuss
current examples of virus–ion channel interactions and the potential of targeting ion channel …
current examples of virus–ion channel interactions and the potential of targeting ion channel …
[HTML][HTML] Viral proteins function as ion channels
… Viral ion channels are short membrane proteins with 50–120 … advances in viral encoded ion
channel proteins (or viroporins), … viral ion channel protein serving as a potential drug target. …
channel proteins (or viroporins), … viral ion channel protein serving as a potential drug target. …
Viroporins: structure, function and potential as antiviral targets
C Scott, S Griffin - Journal of General Virology, 2015 - microbiologyresearch.org
… as an antiviral drug target. This review attempts to summarize our current understanding of
the channel-… Ultimately, given the successes of drugs targeting ion channels in other areas of …
the channel-… Ultimately, given the successes of drugs targeting ion channels in other areas of …
[HTML][HTML] Modulation of adaptive immunity and viral infections by ion channels
K Bohmwald, NMS Gálvez, CA Andrade… - Frontiers in …, 2021 - frontiersin.org
… cells, Ca 2+ channels function can be altered, … ion channels and ion transporters that are
essential for the function of immune cells. Specifically, cation channels and Ca 2+ channels in …
essential for the function of immune cells. Specifically, cation channels and Ca 2+ channels in …
Put a cork in it: Plugging the M2 viral ion channel to sink influenza
… -selective ion channel that is required for virus replication and is an established antiviral target.
… mutations, and ongoing efforts to develop new antivirals that target resistant forms of M2. …
… mutations, and ongoing efforts to develop new antivirals that target resistant forms of M2. …
Genistein as antiviral drug against HIV ion channel
… tool to screen drugs for their potency in inhibition of ion channel activity. The viral protein U-…
that viral ion channels, in general, may be a good target for development of antiviral agents, …
that viral ion channels, in general, may be a good target for development of antiviral agents, …
Molecular design, synthesis and biological evaluation of cage compound-based inhibitors of hepatitis C virus p7 ion channels
VA Shiryaev, EV Radchenko, VA Palyulin… - European Journal of …, 2018 - Elsevier
… with small-molecule inhibitors may provide an attractive option in antiviral development.
The … (and many other ion channels) makes them suitable targets for the cage compound …
The … (and many other ion channels) makes them suitable targets for the cage compound …
[PDF][PDF] Resistance mutations define specific antiviral effects for inhibitors of the hepatitis C virus p7 ion channel
TL Foster, M Verow, AL Wozniak, MJ Bentham… - …, 2011 - Wiley Online Library
… channel function in vitro and virion production in culture, rendering it an attractive antiviral
target.… points26,27 supports a specific antiviral effect, and selection of specific nonsynonymous …
target.… points26,27 supports a specific antiviral effect, and selection of specific nonsynonymous …